Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.72 |
| ▸ | CA6 | P23280 | 5/20 | 0.72 |
| ▸ | CA7 | P43166 | 5/20 | 0.72 |
| ▸ | CA9 | Q16790 | 5/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.72 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.72 |
| ▸ | CA2 | P00918 | 4/20 | 0.72 |
| ▸ | CA4 | P22748 | 4/20 | 0.72 |
| ▸ | CA5A | P35218 | 4/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.72 |
| ▸ | F13A1 | P00488 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | THPO | P40225 | 2/20 | 0.72 |
| ▸ | CASP2 | P42575 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | RECQL | P46063 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | CA3 | P07451 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Spermine SCHEMBL27775510 | 0.86 | CA12 (0.77) | CA12CA6CA7CA9CA14 | |
| SCHEMBL26132507 | 0.85 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| Spermine SCHEMBL30446193 | 0.85 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| Spermine SCHEMBL288720 | 0.85 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| Spermine SCHEMBL8514287 | 0.85 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| Spermine SCHEMBL14965 | 0.85 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| Piperazine SCHEMBL11591607 | 0.82 | CA12 (0.62) | CA12CA6CA7CA9CA14 | |
| Spermidine SCHEMBL2514297 | 0.82 | CA12 (0.88) | CA12CA6CA7CA9CA14 | |
| SCHEMBL3175232 | 0.82 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| SCHEMBL4288395 | 0.82 | CA12 (0.93) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109069470-A | Use of specific benzodihydrofuran lignans for inhibiting breast cancer cell metastasis | 杨宁荪 | 2018-12-21 | — | — | CN | claimed |
| CN-110461322-A | For inhibiting the composition and method of plasma membrane protein 4 | UNIV CALIFORNIA | 2019-11-15 | — | — | CN | disclosed |
| CN-109069470-A | Use of specific benzodihydrofuran lignans for inhibiting breast cancer cell metastasis | 杨宁荪 | 2018-12-21 | — | — | CN | disclosed |
| CN-108069963-A | Pyridopyrimidine derivatives or its salt and its preparation method, pharmaceutical composition and purposes | 清华大学 | 2018-05-25 | — | — | CN | disclosed |
| CN-106715458-A | Cancer vaccine compositions and methods of use thereof | 华盛顿大学 | 2017-05-24 | — | — | CN | disclosed |
| CN-106456735-A | Breast and ovarian cancer vaccines | 华盛顿大学商业中心 | 2017-02-22 | — | — | CN | disclosed |
| CN-106236741-A | For treating the Compounds and methods for of abnormal adrenal cortical cell disease | 密歇根大学董事会 | 2016-12-21 | — | — | CN | disclosed |
| CN-104302283-B | Compounds and methods for treating aberrant adrenocortical cell disorders | 密歇根大学董事会 | 2016-08-24 | — | — | CN | disclosed |
| CN-105452287-A | Immunosuppressive TGF-beta signaling converter | BAYLOR COLLEGE MEDICINE | 2016-03-30 | — | — | CN | disclosed |
| CN-105407914-A | Heparanase expression in human T lymphocytes | BAYLOR COLLEGE MEDICINE | 2016-03-16 | — | — | CN | disclosed |
| US-7208528-B1 | Polyamine analogues as therapeutic and diagnostic agents | MEDIQUEST THERAPEUTICS, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| US-7160923-B1 | Polyamine analogues as therapeutic and diagnostic agents | MEDIQUEST THERAPEUTICS, INC. (US) | 2007-01-09 | — | — | US | disclosed |
| CN-1512982-A | Novel polyamine analogues as therapeutic and diagnostic agents | �ȿ˻�ѧ�ɷ�����˾ | 2004-07-14 | — | — | CN | disclosed |
| US-6646149-B1 | Derivitives of spermine or its N12-t-butyl carbamate | VERMEULIN NICOLAAS M J (US) | 2003-11-11 | — | — | US | disclosed |
| EP-1317424-A2 | POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | MediQuest Therapeutics, Inc. (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2001092218-A2 | POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 2001-12-06 | — | — | WO | disclosed |
| EP-1085011-A1 | Novel polyamine analogues as therapeutic and diagnostic agents | ORIDIGM CORPORATION (US) | 2001-03-21 | — | — | EP | disclosed |
| US-6172261-B1 | BIOSYNTHESIS USING CHAIN EXTENSION | ORIDIGM CORPORATION | 2001-01-09 | — | — | US | disclosed |
| EP-1001927-A2 | NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999003823-A2 | NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 1999-01-28 | — | — | WO | disclosed |