Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.41 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267735 | 0.79 | ADRA2C (0.55) | CYP19A1AGER | |
| SCHEMBL30928337 | 0.79 | CYP19A1 (0.55) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL27775794 | 0.79 | HMOX2 (0.44) | AGERCYP1A2CYP3A4CYP2D6TBXAS1 | |
| SCHEMBL27956540 | 0.77 | CYP19A1 (0.56) | CYP11B1CYP11B2IDO1CYP19A1POLB | |
| SCHEMBL28811703 | 0.76 | IDO1 (0.49) | CYP11B1CYP11B2IDO1CYP19A1 | |
| SCHEMBL27956577 | 0.75 | AGER (0.42) | CYP11B1CYP11B2CYP19A1AGERCYP1A2 | |
| SCHEMBL27956581 | 0.74 | CYP17A1 (0.54) | CYP11B1CYP11B2IDO1CYP19A1CYP3A4 | |
| SCHEMBL27775615 | 0.74 | MAPK1 (0.43) | CYP19A1CYP1A2POLBCYP3A4CYP2D6 | |
| SCHEMBL11384324 | 0.74 | CYP19A1 (0.50) | CYP11B1CYP11B2IDO1CYP19A1CYP3A4 | |
| SCHEMBL28810901 | 0.72 | SMN1; SMN2 (0.45) | CYP11B1CYP11B2CYP19A1AGERCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101519402-B | Thiochromone compound, synthetic method thereof and application thereof in preparation of antifungal drugs | NANJING UNIVERSITY OF TECHNOLOGY | 2010-12-29 | — | — | CN | disclosed |
| CN-101519402-A | Thiochromone compound, synthetic method thereof and application thereof in preparation of antifungal drugs | NANJING UNIVERSITY OF TECHNOLOGY | 2009-09-02 | — | — | CN | disclosed |