Biphenyl

Biphenyl

SCHEMBL27775705

O=S(=O)(O)C(F)(F)F.Sc1cccc2ccccc12.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 5/20 0.45
ACP3 P15309 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP1A2 P05177 1/20 0.36
NR4A1 P22736 1/20 0.36
NR4A2 P43354 1/20 0.36
NR4A3 Q92570 1/20 0.36
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA9 Q16790 3/20 0.36
CA12 O43570 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL6249524 0.94 CYP1A2 (0.41) PTPN1HDAC1HDAC7HDAC8HDAC6
Biphenyl SCHEMBL1050411 0.79 PTPN1 (0.58) PTPN1HDAC1HDAC7HDAC8HDAC6
Trifluoromethanesulfonic Acid SCHEMBL28025897 0.78 CA12 (0.45) PTPN1HDAC8HDAC6KDM4EMEN1
Trifluoromethanesulfonic Acid SCHEMBL6656119 0.78 DNMT1 (0.41) PTPN1HDAC8HDAC6KDM4EMEN1
Biphenyl SCHEMBL27838332 0.77 PTPN1 (0.53) PTPN1HDAC6MEN1KMT2AALDH1A1
Phenanthrene SCHEMBL28237114 0.77 ALDH1A1 (0.52) KDM4EMEN1KMT2AALDH1A1HPGD
Biphenyl SCHEMBL304392 0.77 PTPN1 (0.56) PTPN1HDAC1HDAC7HDAC8HDAC6
Biphenyl SCHEMBL5410059 0.77 PTPN1 (0.56) PTPN1HDAC1HDAC7HDAC8HDAC6
Biphenyl SCHEMBL2192409 0.77 PTPN1 (0.56) PTPN1HDAC1HDAC7HDAC8HDAC6
Trifluoromethanesulfonic Acid SCHEMBL27896491 0.77 CA12 (0.44) PTPN1HDAC8HDAC6KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103102251-B Radiation-ray sensitive composition MITSUBISHI GAS CHEMICAL INC. (JP) 2016-01-20 CN disclosed
CN-101528653-B Radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO 2013-09-11 CN disclosed
CN-103102251-A Radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO 2013-05-15 CN disclosed
CN-101528653-A Radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO (JP) 2009-09-09 CN disclosed