Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL1050411 | 0.98 | PTPN1 (0.58) | PTPN1PTPN5KIF11ALDH1A1TSHR | |
| Biphenyl SCHEMBL304392 | 0.95 | PTPN1 (0.56) | PTPN1PTPN5KIF11ALDH1A1TSHR | |
| Biphenyl SCHEMBL5410059 | 0.95 | PTPN1 (0.56) | PTPN1PTPN5KIF11ALDH1A1TSHR | |
| Biphenyl SCHEMBL27838332 | 0.91 | PTPN1 (0.53) | PTPN1PTPN5KIF11ALDH1A1TSHR | |
| Trifluoromethanesulfonic Acid SCHEMBL31473545 | 0.86 | PTPN1 (0.53) | PTPN1PTPN5KIF11CA1CA2 | |
| Trifluoromethanesulfonic Acid SCHEMBL27707915 | 0.86 | PTPN1 (0.53) | PTPN1PTPN5KIF11CA1CA2 | |
| Biphenyl SCHEMBL30131105 | 0.84 | PTPN1 (0.47) | PTPN1PTPN5KIF11ALDH1A1TSHR | |
| Trifluoromethanesulfonic Acid SCHEMBL27826316 | 0.82 | TSHR (0.48) | PTPN1ALDH1A1TSHRSMN1; SMN2CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL789189 | 0.82 | ALDH1A1 (0.50) | PTPN1ALDH1A1TSHRSMN1; SMN2CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL30552135 | 0.82 | ALDH1A1 (0.50) | PTPN1ALDH1A1TSHRSMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220324891-A1 | COMPOSITIONS AND METHODS FOR PREPARING REGIO- AND STEREOSELECTIVE ALICYCLIC ALKENE ISOTOPOLOGUES AND STEREOISOTOPOMERS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2022-10-13 | — | — | US | disclosed |
| WO-2020257299-A1 | COMPOSITIONS AND METHODS FOR PREPARING REGIO- AND STEREOSELECTIVE ALICYCLIC ALKENE ISOTOPOLOGUES AND STEREOISOTOPOMERS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2020-12-24 | — | — | WO | disclosed |
| US-20190247354-A1 | CREATINE ESTER ANTI-INFLAMMATORY COMPOUNDS AND FORMULATIONS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2019-08-15 | — | — | US | disclosed |
| US-10206897-B2 | Creatine ester anti-inflammatory compounds and formulations | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2019-02-19 | — | — | US | disclosed |
| US-20180153844-A1 | CREATINE ESTER ANTI-INFLAMMATORY COMPOUNDS AND FORMULATIONS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2018-06-07 | — | — | US | disclosed |
| US-9833427-B2 | Creatine ester anti-inflammatory compounds and formulations | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2017-12-05 | — | — | US | disclosed |
| US-20170202241-A1 | CREATINE ESTER PRONUTRIENT COMPOUNDS AND FORMULATIONS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2017-07-20 | — | — | US | disclosed |
| CN-105368029-A | Polymer compositions and method | NOVOMER INC | 2016-03-02 | — | — | CN | disclosed |
| CN-102026954-B | Processes for the preparation of esters | SYNGENTA PARTICIPATIONS AG | 2014-06-04 | — | — | CN | disclosed |
| US-20120289648-A1 | REACTIVE COMPOUNDS ON THE BASIS OF TRANSESTERIFICATION | EVONIK DEGUSSA GMBH (DE) | 2012-11-15 | — | — | US | disclosed |
| US-20070203076-A1 | CREATINE ESTER PRONUTRIENT COMPOUNDS AND FORMULATIONS | VENNERSTROM JONATHAN L | 2007-08-30 | — | — | US | disclosed |
| CN-101003591-A | Resin suitable for an acid generator and a chemically amplified positive resist composition containing the same | SUMITOMO CHEMICAL CO (JP) | 2007-07-25 | — | — | CN | disclosed |
| EP-1324760-B1 | CREATINE ESTER PRONUTRIENT COMPOUNDS AND FORMULATIONS | UNIV NEBRASKA (US) | 2007-06-20 | — | — | EP | disclosed |
| EP-1688139-A1 | Creatine ester pronutrient compounds and formulations | Board of Regents of the University of Nebraska (US) | 2006-08-09 | — | — | EP | disclosed |
| EP-1324760-A4 | CREATINE ESTER PRONUTRIENT COMPOUNDS AND FORMULATIONS | REGENTS OFTHE UNIVERSITY OF NE (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004071406-A2 | CREATINE ESTER ANTI-INFLAMMATORY COMPOUNDS AND FORMULATIONS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2004-08-26 | — | — | WO | disclosed |
| US-20030212130-A1 | Creatine ester anti-inflammatory compounds and formulations | NEBRASKA, UNIVERSITY OF MEDICAL CENTER | 2003-11-13 | — | — | US | disclosed |
| US-20030212136-A1 | Creatine ester pronutrient compounds and formulations | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2003-11-13 | — | — | US | disclosed |
| EP-1324760-A1 | CREATINE ESTER PRONUTRIENT COMPOUNDS AND FORMULATIONS | Board of Regents of the University of Nebraska (US) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002022135-A1 | CREATINE ESTER PRONUTRIENT COMPOUNDS AND FORMULATIONS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212130-A1 | Creatine ester anti-inflammatory compounds and formulations | CKMT1A; CKMT1B, CPT1B, CRAT | PTPN1 4574/4885PTPN5 4391/4885KIF11 2753/4885 |
| US-20180153844-A1 | CREATINE ESTER ANTI-INFLAMMATORY COMPOUNDS AND FORMULATIONS | CKMT1A; CKMT1B, CPT1B, CRAT | PTPN1 4574/4885PTPN5 4391/4885KIF11 2753/4885 |
| US-20190247354-A1 | CREATINE ESTER ANTI-INFLAMMATORY COMPOUNDS AND FORMULATIONS | CKMT1A; CKMT1B, CPT1B, CRAT | PTPN1 4574/4885PTPN5 4391/4885KIF11 2753/4885 |
| US-20170202241-A1 | CREATINE ESTER PRONUTRIENT COMPOUNDS AND FORMULATIONS | CKMT1A; CKMT1B, CPT1B, PYGM | PTPN1 4844/4885PTPN5 4770/4885KIF11 1261/4885 |
| US-10206897-B2 | Creatine ester anti-inflammatory compounds and formulations | CKMT1A; CKMT1B, CPT1B, CRAT | PTPN1 4574/4885PTPN5 4391/4885KIF11 2753/4885 |
| US-20070203076-A1 | CREATINE ESTER PRONUTRIENT COMPOUNDS AND FORMULATIONS | CKMT1A; CKMT1B, CPT1B, PYGM | PTPN1 4844/4885PTPN5 4770/4885KIF11 1261/4885 |
| US-20030212136-A1 | Creatine ester pronutrient compounds and formulations | CKMT1A; CKMT1B, CPT1B, PYGM | PTPN1 4829/4885PTPN5 4736/4885KIF11 1417/4885 |
| US-20220324891-A1 | COMPOSITIONS AND METHODS FOR PREPARING REGIO- AND STEREOSELECTIVE ALICYCLIC ALKENE ISOTOPOLOGUES AND STEREOISOTOPOMERS | ADRA2C, HTR2C, HTR1B | PTPN1 3614/4885PTPN5 3940/4885KIF11 3170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.