Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.31 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264397 | 0.81 | — | — | |
| SCHEMBL736908 | 0.81 | L3MBTL3 (0.32) | — | |
| SCHEMBL735435 | 0.79 | L3MBTL3 (0.31) | — | |
| SCHEMBL737602 | 0.79 | L3MBTL3 (0.31) | — | |
| SCHEMBL739062 | 0.79 | L3MBTL3 (0.31) | — | |
| SCHEMBL9469528 | 0.77 | — | — | |
| SCHEMBL735235 | 0.75 | CYP2D6 (0.33) | TDP1 | |
| SCHEMBL206897 | 0.75 | CYP2D6 (0.33) | TDP1 | |
| SCHEMBL4159670 | 0.75 | CYP2D6 (0.33) | TDP1 | |
| SCHEMBL738007 | 0.74 | L3MBTL1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516888-A | Pyrazolo [1, 5-a] pyrimidine derivatives and their therapeutic use | NOVARTIS AG (CH) | 2009-08-26 | — | — | CN | disclosed |