Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | PTPRF | P10586 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | PTPRE | P23469 | 1/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.31 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demannose SCHEMBL27878620 | 0.93 | L3MBTL1 (0.41) | L3MBTL1LMNATDP1PDE4AGAA | |
| Demannose SCHEMBL27869816 | 0.92 | ALDH1A1 (0.35) | L3MBTL1LMNATDP1GAACYP1A2 | |
| Pyrene SCHEMBL14645754 | 0.85 | L3MBTL1 (0.37) | L3MBTL1LMNATDP1PDE4AGAA | |
| Pyrene SCHEMBL28202974 | 0.85 | L3MBTL1 (0.37) | L3MBTL1LMNATDP1PDE4AGAA | |
| Demannose SCHEMBL27784462 | 0.83 | LMNA (0.50) | L3MBTL1LMNATDP1PDE4AGAA | |
| Anthraquinone SCHEMBL28146014 | 0.83 | MEN1 (0.41) | L3MBTL1LMNATDP1CYP1A2PTPRC | |
| Demannose SCHEMBL6515282 | 0.83 | L3MBTL1 (0.38) | L3MBTL1LMNATDP1PDE4AGAA | |
| Demannose SCHEMBL3515070 | 0.83 | TDP1 (0.38) | L3MBTL1LMNATDP1PDE4AGAA | |
| Demannose SCHEMBL28198426 | 0.81 | LMNA (0.48) | L3MBTL1LMNATDP1PDE4AUSP2 | |
| Demannose SCHEMBL14958551 | 0.81 | LMNA (0.58) | L3MBTL1LMNATDP1PDE4AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573981-A | Combination therapy with anti-CD 40 antibodies | 鳄鱼生物科学公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-102406944-A | Antibodies to internalization of KU70 | BIOINVENT INT AB | 2012-04-11 | — | — | CN | disclosed |
| CN-101466405-A | Antibodies to internalization of KU70 | BIOINVENT INT AB SE (SE) | 2009-06-24 | — | — | CN | disclosed |