Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27488808 | 0.77 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL28552239 | 0.73 | SOS1 (0.37) | NR1H2 | |
| SCHEMBL26089899 | 0.72 | NR1H2 (0.41) | NR1H2 | |
| SCHEMBL12017166 | 0.71 | NR1H2 (0.36) | NR1H2 | |
| SCHEMBL34473271 | 0.69 | NR1H2 (0.39) | NR1H2 | |
| SCHEMBL18821254 | 0.69 | CRBN (0.31) | — | |
| SCHEMBL9825904 | 0.69 | — | — | |
| SCHEMBL19919573 | 0.68 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL15155174 | 0.68 | DDB1 (0.33) | — | |
| SCHEMBL28257989 | 0.68 | BUB1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101511799-B | Cyclic amine compound | DAIICHI SANKYO CO LTD | 2012-05-30 | — | — | CN | disclosed |
| CN-101511799-A | Cyclic amine compound | DAIICHI SANKYO CO LTD (JP) | 2009-08-19 | — | — | CN | disclosed |