SCHEMBL2777667

SCHEMBL2777667

C=CC(=O)OC(F)(F)C(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.36
ALDH1A1 P00352 5/20 0.36
HSD17B10 Q99714 2/20 0.36
TP53 P04637 3/20 0.31
HIF1A Q16665 3/20 0.31
CYP3A4 P08684 2/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL64755 0.83 TSHR (0.34) TSHRALDH1A1HSD17B10TP53HIF1A
SCHEMBL16223137 0.80
SCHEMBL676519 0.79 TSHR (0.41) TSHRALDH1A1HSD17B10TP53HIF1A
SCHEMBL692689 0.78 THRB (0.31)
SCHEMBL5480123 0.78 THRB (0.31)
SCHEMBL15157148 0.78 THRB (0.31)
SCHEMBL27469564 0.78 ALDH1A1 (0.44) TSHRALDH1A1HSD17B10
SCHEMBL3902256 0.78 TSHR (0.31) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9679277 0.77 TSHR (0.32) TSHR
SCHEMBL377429 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116496749-A Low-refractive-index photo-curing adhesive and preparation method thereof 惠州市杜科新材料有限公司 2023-07-28 CN claimed
US-20050048200-A1 PROCESS FOR PREPARING AN OPTICAL WAVEGUIDE COMPONENT FROM ACRYLATE/TITANIUM ALKOXIDE COMPOSITE MATERIAL AND THE PREPARED OPTICAL WAVEGUIDE COMPONENT CHANG CHUN PLASTICS CO., LTD. (TW) 2005-03-03 US claimed
US-6852358-B1 Process for preparing an optical waveguide component from acrylate/titanium alkoxide composite material and the prepared optical waveguide component CHANG CHUN PLASTICS CO., LTD. (TW) 2005-02-08 US claimed
US-6519380-B2 Athermalized integrated optical waveguide devices CORNING INCORPORATED 2003-02-11 US claimed
US-5690863-A FLUORINE-CONTAINING (METH)ACRYLATES OPTICAL POLYMER RESEARCH, INC. (US) 1997-11-25 US claimed
CN-116496749-A Low-refractive-index photo-curing adhesive and preparation method thereof 惠州市杜科新材料有限公司 2023-07-28 CN disclosed
US-9927705-B2 Additive for resist underlayer film-forming composition and resist underlayer film-forming composition containing the same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-27 US disclosed
US-20160147152-A1 ADDITIVE FOR RESIST UNDERLAYER FILM-FORMING COMPOSITION AND RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING THE SAME NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-05-26 US disclosed
US-9165782-B2 Additive for resist underlayer film-forming composition and resist underlayer film-forming composition containing the same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-10-20 US disclosed
US-20150247958-A1 ANTI-REFLECTION FILM, MANUFACTURING METHOD THEREOF, POLARIZING PLATE AND TRANSMISSION TYPE LCD TOPPAN PRINTING CO., LTD. (JP) 2015-09-03 US disclosed
US-20140287589-A1 ADDITIVE FOR RESIST UNDERLAYER FILM-FORMING COMPOSITION AND RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING THE SAME NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-09-25 US disclosed
EP-1306897-B1 Method of making electrode-to-electrode bond structure FUJITSU LTD (JP) 2013-12-11 EP disclosed
US-6852358-B1 Process for preparing an optical waveguide component from acrylate/titanium alkoxide composite material and the prepared optical waveguide component CHANG CHUN PLASTICS CO., LTD. (TW) 2005-02-08 US disclosed
US-20040106232-A1 Method of making electrode-to-electrode bond structure and electrode-to-electrode bond structure made thereby FUJITSU LIMITED (JP) 2004-06-03 US disclosed
US-6670264-B2 Method of making electrode-to-electrode bond structure and electrode-to-electrode bond structure made thereby FUJITSU LIMITED (JP) 2003-12-30 US disclosed
EP-1306897-A2 Method of making electrode-to-electrode bond structure and electrode-to-electrode bond structure made thereby FUJITSU LIMITED (JP) 2003-05-02 EP disclosed
US-20030080397-A1 Method of making electrode-to-electrode bond structure and electrode-to-electrode bond structure made thereby FUJITSU LIMITED (JP) 2003-05-01 US disclosed
US-5212762-A Optical fibers MITSUBISHI RAYON CO., LTD. (JP) 1993-05-18 US disclosed
EP-0488189-A1 Plastic-clad silica (PCS) fibers and methods and apparatuses for producing the same MITSUBISHI RAYON CO., LTD. (JP) 1992-06-03 EP disclosed
US-4131471-A HALOALKYL ACRYLATE ESTER POLYMER, PROTECTIVE COLLOID POLAROID CORPORATION (US) 1978-12-26 US disclosed