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Tert-Butyl Formate

Tert-Butyl Formate

SCHEMBL27776862

CC(C)(C)OC=O.COC(=O)C(C)n1c(=O)[nH]c2ccc(Cl)cc21

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ B3GNT2 Q9NY97 12/20 0.46
▸ PGR P06401 4/20 0.42
▸ DAO P14920 1/20 0.42
▸ MDM2 Q00987 1/20 0.39
▸ CBX7 O95931 1/20 0.39
▸ CDYL2 Q8N8U2 1/20 0.39
▸ CDYL Q9Y232 1/20 0.39
▸ CDY1; CDY1B Q9Y6F8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butyl Formate SCHEMBL27776805 0.79 B3GNT2 (0.40) B3GNT2PGRDAOMDM2CBX7
Tert-Butyl Formate SCHEMBL27755984 0.77 MDM2 (0.55) B3GNT2PGRDAOMDM2CBX7
SCHEMBL639581 0.76 DAO (0.55) B3GNT2PGRDAOMDM2
SCHEMBL640633 0.72 B3GNT2 (0.54) B3GNT2PGRDAOMDM2
SCHEMBL2968866 0.72 PGR (0.72) B3GNT2PGRDAO
SCHEMBL27755968 0.71 B3GNT2 (0.44) B3GNT2PGRDAOMDM2CBX7
SCHEMBL642977 0.68 LMNA (0.44) MDM2
SCHEMBL16997516 0.68 DAO (0.60) PGRDAOCBX7CDYL2CDYL
SCHEMBL2308145 0.67 POLB (0.57) B3GNT2PGRDAOMDM2
SCHEMBL19410170 0.67 POLB (0.57) B3GNT2PGRDAOMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101528712-A Substituted benzimidazolone derivatives, medicaments containing them and the use thereof ABBOTT GMBH & CO KG (DE) 2009-09-09 — — CN disclosed
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