Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | B3GNT2 | Q9NY97 | 13/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 3/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL639581 | 0.83 | DAO (0.55) | B3GNT2DAOMDM2PGRPSMB8 | |
| SCHEMBL640651 | 0.80 | POLB (0.59) | B3GNT2DAOMDM2 | |
| SCHEMBL2968866 | 0.78 | PGR (0.72) | B3GNT2DAOPGRPSMB8 | |
| SCHEMBL640117 | 0.77 | DAO (0.51) | B3GNT2DAOMDM2PGR | |
| SCHEMBL640608 | 0.76 | MDM2 (0.65) | DAOMDM2PGR | |
| SCHEMBL319785 | 0.76 | DAO (0.52) | B3GNT2DAOPGRPSMB8 | |
| SCHEMBL27755968 | 0.75 | B3GNT2 (0.44) | B3GNT2DAOMDM2PGR | |
| SCHEMBL641668 | 0.74 | GABRP (0.51) | B3GNT2DAOMDM2PGR | |
| SCHEMBL640979 | 0.73 | CBX7 (0.44) | B3GNT2DAOMDM2PGR | |
| SCHEMBL16997516 | 0.73 | DAO (0.60) | DAOPGRPSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119676-B2 | Substituted benzimidazolone derivatives, medicaments comprising them and their use | Abbott GmbH & Co. HG (DE) | 2012-02-21 | — | — | US | disclosed |