Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | F12 | P00748 | 3/20 | 0.35 |
| ▸ | F11 | P03951 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.35 |
| ▸ | F7 | P08709 | 3/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.35 |
| ▸ | F9 | P00740 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 3/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.33 |
| ▸ | GRB2 | P62993 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27756043 | 0.82 | PARP1 (0.33) | F2PRSS1PARP1 | |
| SCHEMBL27776882 | 0.81 | SMN1; SMN2 (0.33) | F2PRSS1PARP1 | |
| SCHEMBL16359592 | 0.79 | ACE (0.39) | ACEGRB2 | |
| SCHEMBL11012174 | 0.78 | ACE (0.43) | ACEREN | |
| SCHEMBL10431341 | 0.78 | ACE (0.33) | ACEREN | |
| SCHEMBL11009837 | 0.78 | ACE (0.34) | ACERENGRB2 | |
| SCHEMBL31020879 | 0.77 | ACE (0.38) | ACEREN | |
| SCHEMBL13363654 | 0.76 | ACE (0.49) | ACERENGRB2 | |
| SCHEMBL31020877 | 0.75 | ACE (0.47) | ACEGRB2 | |
| SCHEMBL8252710 | 0.75 | REN (0.38) | ACERENGRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0143746-A2 | 5-Amino 4-hydroxy-valeryl-substituted derivatives | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | disclosed |