Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 3/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27756045 | 0.99 | SOS1 (0.38) | SOS1KRASSMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL19327375 | 0.92 | SOS1 (0.36) | SOS1KRASTDP1KMT2AHSD17B10 | |
| SCHEMBL3062665 | 0.89 | LMNA (0.37) | SOS1KRASSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL2735529 | 0.84 | TAS1R3 (0.40) | L3MBTL1TDP1 | |
| Histidine SCHEMBL27762881 | 0.82 | TPH1 (0.38) | — | |
| SCHEMBL9031805 | 0.82 | POLB (0.45) | KMT2A | |
| SCHEMBL21841466 | 0.81 | SOS1 (0.32) | SOS1KRAS | |
| SCHEMBL24270549 | 0.81 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL14065661 | 0.81 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL23806754 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101531637-A | A novel compound capable of restraining and blocking M2 ion channel activity and application thereof | CHINESE ACADEMY OF SCIENCES GU | 2009-09-16 | — | — | CN | claimed |
| CN-101531637-B | A novel compound capable of restraining and blocking M2 ion channel activity and application thereof | CHINESE ACADEMY OF SCIENCES GUANGZHOU INST OF BIOMEDICINE AND HEALTH | 2011-07-13 | — | — | CN | disclosed |
| CN-101531637-A | A novel compound capable of restraining and blocking M2 ion channel activity and application thereof | CHINESE ACADEMY OF SCIENCES GU | 2009-09-16 | — | — | CN | disclosed |