Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL324038 | 0.82 | KMO (1.00) | KMOALDH1A1CYP1A2RECQLDAO | |
| SCHEMBL31427168 | 0.82 | KMO (1.00) | KMOALDH1A1CYP1A2RECQLDAO | |
| SCHEMBL20083689 | 0.81 | KMO (0.66) | KMOALDH1A1CYP1A2RECQLDAO | |
| SCHEMBL8889255 | 0.78 | KMO (0.74) | KMOCYP1A2RECQLKMT2ASMN1; SMN2 | |
| SCHEMBL22965232 | 0.77 | KMO (0.82) | KMOCYP1A2RECQLDAOPOLB | |
| SCHEMBL22572429 | 0.74 | KMO (0.68) | KMOCYP1A2RECQLKMT2ASMN1; SMN2 | |
| SCHEMBL28736790 | 0.74 | KMO (0.68) | KMOCYP1A2RECQLKMT2ASMN1; SMN2 | |
| SCHEMBL22965272 | 0.73 | KMO (0.58) | KMOCYP1A2RECQLKMT2AMEN1 | |
| SCHEMBL29544889 | 0.72 | KMO (0.71) | KMOCYP1A2RECQLKMT2ASMN1; SMN2 | |
| SCHEMBL3374171 | 0.72 | KMO (0.71) | KMOCYP1A2RECQLKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679370-A | Novel vanilloid receptor ligands and the use thereof for the production of pharmaceuticals | GRUENENTHAL GMBH | 2010-03-24 | — | — | CN | disclosed |