Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 6/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28736790 | 0.92 | KMO (0.68) | KMOLMNACYP1A2RECQLKDM4E | |
| SCHEMBL324038 | 0.85 | KMO (1.00) | KMOCYP1A2RECQLDAOPOLB | |
| SCHEMBL31427168 | 0.85 | KMO (1.00) | KMOCYP1A2RECQLDAOPOLB | |
| SCHEMBL2594606 | 0.83 | KMO (0.59) | KMOLMNACYP1A2RECQLKDM4E | |
| SCHEMBL22572429 | 0.80 | KMO (0.68) | KMOCYP1A2RECQLDAOPOLB | |
| SCHEMBL22965232 | 0.79 | KMO (0.82) | KMOCYP1A2RECQLKDM4EDAO | |
| SCHEMBL29209107 | 0.79 | KMO (0.60) | KMOLMNAKDM4E | |
| SCHEMBL27777613 | 0.78 | KMO (0.69) | KMOCYP1A2RECQLDAOPOLB | |
| SCHEMBL31429458 | 0.78 | KMO (0.65) | KMOCYP1A2RECQLDAOPOLB | |
| SCHEMBL20083661 | 0.78 | CYP1A2 (0.62) | KMOCYP1A2RECQLDAOPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793565-B1 | MCL-1 INHIBITORS | GILEAD SCIENCES INC (US) | 2022-01-05 | — | — | EP | disclosed |
| WO-1997012884-A1 | HERBICIDAL 6-HETEROCYCLIC INDAZOLE DERIVATIVES | FMC CORPORATION (US) | 1997-04-10 | — | — | WO | disclosed |