Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.71 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3374171 | 1.00 | KMO (0.71) | KMORECQLPOLBHSD17B10NPC1 | |
| SCHEMBL8999792 | 0.84 | KMO (0.59) | KMORECQLPOLBHSD17B10NPC1 | |
| SCHEMBL2594606 | 0.84 | KMO (0.59) | KMORECQLPOLBHSD17B10NPC1 | |
| SCHEMBL324038 | 0.83 | KMO (1.00) | KMORECQLPOLBHSD17B10TSHR | |
| SCHEMBL31427168 | 0.83 | KMO (1.00) | KMORECQLPOLBHSD17B10TSHR | |
| SCHEMBL12892436 | 0.81 | POLB (0.56) | KMORECQLPOLBHSD17B10NPC1 | |
| SCHEMBL31602336 | 0.81 | KMO (0.56) | KMORECQLPOLBHSD17B10NPC1 | |
| SCHEMBL14354840 | 0.80 | KMO (0.55) | KMORECQLPOLBHSD17B10NPC1 | |
| SCHEMBL2589000 | 0.80 | RAB9A (0.62) | KMORECQLPOLBHSD17B10NPC1 | |
| SCHEMBL22965232 | 0.80 | KMO (0.82) | KMORECQLPOLBHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111513-A1 | COMPOUNDS USEFUL IN THE MODULATION OF KLHDC1 AND KLHDC2 ACTIVITY | NURIX THERAPEUTICS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| CN-114761082-A | Azepane derivatives | 日本化学药品株式会社 | 2022-07-15 | — | — | CN | disclosed |
| CN-114044800-A | Aryl, heteroaryl and heterocyclic compounds for the treatment of medical disorders | 艾其林医药公司 | 2022-02-15 | — | — | CN | disclosed |