Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | PTPRA | P18433 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27954184 | 0.79 | PTPRA (0.47) | CYP1A2PGRADORA3PTGS1SLC6A2 | |
| SCHEMBL27613846 | 0.74 | CYP3A4 (0.41) | CYP1A2LMNAMAOBCYP2D6 | |
| SCHEMBL27613874 | 0.74 | CYP3A4 (0.41) | CYP1A2LMNAMAOBCYP2D6 | |
| SCHEMBL10237746 | 0.70 | PGR (0.43) | CYP1A2PGRADORA3PTGS1SLC6A2 | |
| SCHEMBL27766035 | 0.70 | RIPK1 (0.44) | RAB9AALDH1A1POLBMAPT | |
| SCHEMBL14748865 | 0.70 | CYP1A2 (0.43) | CYP1A2PGRADORA3PTGS1SLC6A2 | |
| SCHEMBL1903216 | 0.69 | GRM5 (0.45) | CYP1A2PGRADORA3PTGS1SLC6A2 | |
| SCHEMBL10202636 | 0.69 | PGR (0.45) | CYP1A2PGRADORA3PTGS1SLC6A2 | |
| SCHEMBL740172 | 0.68 | ALDH1A1 (0.46) | CYP1A2PGRADORA3PTGS1SLC6A2 | |
| SCHEMBL12164511 | 0.68 | NPC1 (0.49) | CYP1A2PGRADORA3PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679382-A | 3-imidazolyl-indoles for the treatment of proliferative diseases | NOVARTIS AG | 2010-03-24 | — | — | CN | disclosed |