Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19392447 | 0.81 | ACHE (0.53) | ACHESTAT3TRPA1GRIA4CHRNA7 | |
| SCHEMBL18545311 | 0.80 | TRPA1 (0.39) | ACHETRPA1ESR1ESR2 | |
| SCHEMBL4582172 | 0.79 | TRPA1 (0.63) | TRPA1ALDH1A1 | |
| SCHEMBL2418955 | 0.79 | TRPA1 (0.63) | TRPA1ALDH1A1 | |
| SCHEMBL11558117 | 0.78 | ACHE (0.39) | ACHESTAT3CHRNA7ALOX5TDP1 | |
| SCHEMBL9630740 | 0.77 | NOS2 (0.37) | TRPA1ALDH1A1 | |
| SCHEMBL6546413 | 0.77 | TRPA1 (0.55) | ACHESTAT3TRPA1CNR1CNR2 | |
| SCHEMBL11241173 | 0.77 | ESR1 (0.52) | ESR1ESR2ALOX5 | |
| SCHEMBL11235771 | 0.77 | TRPA1 (0.50) | TRPA1GRIA4ALDH1A1 | |
| SCHEMBL6113339 | 0.77 | STAT3 (0.50) | ACHESTAT3TRPA1GRIA4CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101553214-A | Compositions and methods for treating, controlling, reducing, ameliorating, or preventing allergy | BAUSCH & LOMB (US) | 2009-10-07 | — | — | CN | disclosed |
| CN-101528208-A | Compositions and methods for treating or preventing glaucoma or its progression | BAUSCH & LOMB (US) | 2009-09-09 | — | — | CN | disclosed |