SCHEMBL1532813

SCHEMBL1532813

C=C(C)C(=O)OCCOC(=O)C(C)=CCC

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.58
TSHR P16473 4/20 0.52
ALDH1A1 P00352 4/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
GLO1 Q04760 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12984317 0.90 THRB (0.42) THRBTSHRALDH1A1CYP2D6CYP2C19
SCHEMBL28977190 0.85 THRB (0.53) THRBTSHRALDH1A1CYP2D6CYP2C19
Ethylene Glycol SCHEMBL2696754 0.84 THRB (0.38) THRBTSHRALDH1A1CYP2D6CYP2C19
SCHEMBL3807932 0.82 TSHR (0.59) THRBTSHRALDH1A1CYP2D6CYP2C19
SCHEMBL10621006 0.82 HCAR2 (0.41) THRBTSHRALDH1A1CYP2D6CYP2C19
SCHEMBL15074980 0.82 THRB (0.59) THRBTSHRALDH1A1CYP2D6CYP2C19
SCHEMBL284255 0.82 THRB (0.59) THRBTSHRALDH1A1CYP2D6CYP2C19
SCHEMBL5187340 0.82 THRB (0.64) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL7535767 0.82 HCAR2 (0.41) THRBTSHRALDH1A1CYP2D6CYP2C19
SCHEMBL15055177 0.81 THRB (0.55) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116782436-A Silver nanowire heating element and preparation method and application thereof 浙江大华技术股份有限公司 2023-09-19 CN disclosed
US-9248216-B2 Medical devices for delivery of therapeutic agents BOSTON SCIENTIFIC SCIMED, INC. (US) 2016-02-02 US disclosed
US-20130164348-A1 MEDICAL DEVICES FOR DELIVERY OF THERAPEUTIC AGENTS BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-06-27 US disclosed
US-8361143-B2 Medical devices for delivery of therapeutic agents BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-01-29 US disclosed
US-8211455-B2 Implantable or insertable medical devices for controlled delivery of a therapeutic agent BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-07-03 US disclosed
US-20110123594-A1 Implantable or Insertable Medical Devices For Controlled Delivery of a Therapeutic Agent BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-05-26 US disclosed
US-7939094-B2 Comprises implantable/insertable implants (catheter, stents) BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-05-10 US disclosed
US-7923509-B2 Drug delivery compositions and medical devices containing block copolymer BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-04-12 US disclosed
US-7901702-B2 Implantable or insertable medical devices for controlled delivery of a therapeutic agent BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-03-08 US disclosed
US-20100092540-A1 DRUG DELIVERY COMPOSITIONS AND MEDICAL DEVICES CONTAINING BLOCK COPOLYMER BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-04-15 US disclosed
US-20030228346-A1 Sustained release of superoxide dismutase mimics from implantable or insertable medical devices BOSTON SCIENTIFIC SCIMED, INC. 2003-12-11 US disclosed
WO-2003090806-A1 MODULATION OF THERAPEUTIC AGENT RELEASE FROM A POLYMERIC CARRIER USING SOLVENT-BASED TECHNIQUES SCIMED LIFE SYSTEMS, INC. (US) 2003-11-06 WO disclosed
US-20030203000-A1 Modulation of therapeutic agent release from a polymeric carrier using solvent-based techniques BOSTON SCIENTIFIC SCIMED, INC. 2003-10-30 US disclosed
US-20030171496-A1 Drug delivery compositions and medical devices containing block copolymer PINCHUK LEONARD (US) 2003-09-11 US disclosed
EP-1341565-A2 DRUG DELIVERY COMPOSITIONS AND COATED MEDICAL DEVICES Boston Scientific Limited (BB) 2003-09-10 EP disclosed
WO-2003061718-A2 MEDICAL ARTICLES HAVING ENZYMATIC SURFACES FOR LOCALIZED THERAPY SCIMED LIFE SYSTEMS, INC. (US) 2003-07-31 WO disclosed
US-20030138415-A1 Medical articles having enzymatic surfaces for localized therapy BOSTON SCIENTIFIC SCIMED, INC. 2003-07-24 US disclosed
US-6545097-B2 Biocompatible block copolymer comprising one or more elastomeric blocks and one or more thermoplastic blocks connected by a seed polymer SCIMED LIFE SYSTEMS, INC. 2003-04-08 US disclosed
US-20020107330-A1 Drug delivery compositions and medical devices containing block copolymer BOSTON SCIENTIFIC SCIMED, INC. 2002-08-08 US disclosed
WO-2002047731-A2 DRUG DELIVERY COMPOSITIONS AND COATED MEDICAL DEVICES SCIMED LIFE SYSTEMS, INC. (US) 2002-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100092540-A1 DRUG DELIVERY COMPOSITIONS AND MEDICAL DEVICES CONTAINING BLOCK COPOLYMER VEGFA, VMA21, ABCB1 THRB 487/4885TSHR 3134/4885ALDH1A1 2756/4885
US-20030203000-A1 Modulation of therapeutic agent release from a polymeric carrier using solvent-based techniques ABCB11, LPXN, LIPA THRB 2666/4885TSHR 1872/4885ALDH1A1 3437/4885
US-20030228346-A1 Sustained release of superoxide dismutase mimics from implantable or insertable medical devices SOD1, SOD3, CAT THRB 3358/4885TSHR 3220/4885ALDH1A1 284/4885
US-20030138415-A1 Medical articles having enzymatic surfaces for localized therapy CYP21A2, CYP17A1, MGAM THRB 2797/4885TSHR 2347/4885ALDH1A1 1420/4885
US-20110123594-A1 Implantable or Insertable Medical Devices For Controlled Delivery of a Therapeutic Agent MIF, PAICS, IDUA THRB 1955/4885TSHR 2108/4885ALDH1A1 1259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.