Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27778359 | 0.83 | KMT2A (0.52) | KDM2BMEN1KMT2AALDH1A1 | |
| SCHEMBL4079510 | 0.81 | KDM2B (0.44) | KDM2BMEN1KMT2AALDH1A1TAS1R3 | |
| SCHEMBL2321941 | 0.80 | MEN1 (0.50) | MEN1KMT2AALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL1857032 | 0.80 | MEN1 (0.50) | MEN1KMT2AALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL27751800 | 0.78 | ALDH1A1 (0.49) | KDM2BMEN1KMT2AALDH1A1 | |
| SCHEMBL27689722 | 0.78 | ALDH1A1 (0.49) | KDM2BMEN1KMT2AALDH1A1 | |
| SCHEMBL27778356 | 0.76 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27778358 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1 | |
| SCHEMBL28083389 | 0.76 | KDM2B (0.42) | KDM2BALDH1A1 | |
| SCHEMBL3968256 | 0.76 | ALDH1A1 (0.48) | KDM2BMEN1KMT2AALDH1A1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101528723-B | Renin inhibitors | VITAE PHARMACEUTICALS INC | 2013-04-10 | — | — | CN | disclosed |
| CN-101528723-A | Renin inhibitors | VITAE PHARMACEUTICALS INC (US) | 2009-09-09 | — | — | CN | disclosed |