Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.41 |
| ▸ | MGLL | Q99685 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15260632 | 0.81 | STS (0.49) | HSD11B1 | |
| SCHEMBL15260631 | 0.81 | STS (0.49) | HSD11B1 | |
| SCHEMBL28083398 | 0.79 | KDM2B (0.36) | KDM2BHSD11B1ALDH1A1L3MBTL1GAA | |
| SCHEMBL27778359 | 0.76 | KMT2A (0.52) | KDM2BHSD11B1MGLLALDH1A1GAA | |
| SCHEMBL27968913 | 0.76 | MGLL (0.44) | KDM2BMGLLALDH1A1GAA | |
| SCHEMBL28456040 | 0.76 | HSD11B1 (0.52) | HSD11B1MGLLALDH1A1 | |
| SCHEMBL15229313 | 0.76 | HSD11B1 (0.52) | HSD11B1MGLLALDH1A1 | |
| SCHEMBL27778357 | 0.76 | KDM2B (0.40) | KDM2BALDH1A1 | |
| SCHEMBL28138009 | 0.76 | SLC6A2 (0.41) | — | |
| SCHEMBL28021721 | 0.75 | MGLL (0.57) | HSD11B1MGLLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507926-B | Serine/threonine kinase inhibitors | 阵列生物制药公司 | 2016-08-31 | — | — | CN | disclosed |