Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2395691 | 0.79 | ALDH1A1 (0.41) | F2RKDM4EALDH1A1MAPK1CASP1 | |
| SCHEMBL27778508 | 0.79 | NCF1 (0.47) | NCF1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20871855 | 0.76 | CNR1 (0.51) | ALDH1A1MAPK1 | |
| SCHEMBL3039488 | 0.75 | ALDH1A1 (0.46) | KDM4EALDH1A1L3MBTL1CYP1A2CYP2E1 | |
| SCHEMBL3046454 | 0.72 | ALDH1A1 (0.43) | KDM4EALDH1A1L3MBTL1CYP1A2CYP2E1 | |
| SCHEMBL30301243 | 0.72 | NCF1 (0.59) | F2RNCF1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9420844 | 0.72 | NCF1 (0.59) | F2RNCF1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL20871193 | 0.70 | EPHX2 (0.45) | KDM4ECRHR1MEN1KMT2A | |
| SCHEMBL22340417 | 0.69 | EPHX2 (0.43) | KDM4ECRHR1MEN1KMT2A | |
| SCHEMBL4510042 | 0.68 | CRHR1 (0.50) | KDM4EALDH1A1CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679363-B | Novel pyrimidine compound having benzyl(heterocyclicmethyl)amine structure and pharmaceutical product containing the same | KOWA CO | 2013-06-05 | — | — | CN | disclosed |
| CN-101679363-A | Novel pyrimidine compound having benzyl(heterocyclicmethyl)amine structure and pharmaceutical product containing the same | KOWA CO | 2010-03-24 | — | — | CN | disclosed |