Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13394232 | 0.82 | ALDH1A1 (0.46) | LMNATP53CYP3A4TSHRKDM4E | |
| SCHEMBL18088066 | 0.79 | ALDH1A1 (0.46) | LMNATP53CYP3A4TSHRKDM4E | |
| SCHEMBL18134248 | 0.79 | ALDH1A1 (0.46) | LMNATP53CYP3A4TSHRKDM4E | |
| SCHEMBL29788008 | 0.74 | HDAC4 (0.53) | LMNAKDM4EALDH1A1ERN1HPGD | |
| SCHEMBL4579619 | 0.74 | HDAC4 (0.53) | LMNAKDM4EALDH1A1ERN1HPGD | |
| SCHEMBL29364192 | 0.74 | HDAC4 (0.53) | LMNAKDM4EALDH1A1ERN1HPGD | |
| SCHEMBL1370802 | 0.74 | HDAC4 (0.53) | LMNAKDM4EALDH1A1ERN1HPGD | |
| SCHEMBL642228 | 0.73 | HDAC4 (0.58) | LMNAKDM4EALDH1A1ERN1HPGD | |
| SCHEMBL7868950 | 0.72 | CYP1A1 (0.54) | LMNATP53CYP3A4TSHRKDM4E | |
| SCHEMBL7260001 | 0.72 | ERN1 (0.49) | LMNAKDM4EALDH1A1ERN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101495183-A | Treating muscular disorders and improving muscular function | DSM IP ASSETS BV (NL) | 2009-07-29 | — | — | CN | disclosed |