Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13224764 | 0.83 | KDM4E (0.69) | ALDH1A1LMNATP53CYP3A4TSHR | |
| SCHEMBL27779575 | 0.82 | LMNA (0.47) | ALDH1A1LMNATP53CYP3A4TSHR | |
| SCHEMBL13394230 | 0.82 | TRPA1 (0.41) | ALDH1A1TSHRTUBB1TUBB4ATUBB | |
| SCHEMBL13394231 | 0.81 | TUBB1 (0.35) | KDM4ETUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL13394234 | 0.78 | ALOX5 (0.34) | ALDH1A1LMNAKDM4EHPGDTUBB1 | |
| SCHEMBL18134248 | 0.77 | ALDH1A1 (0.46) | ALDH1A1LMNATP53CYP3A4TSHR | |
| SCHEMBL18088066 | 0.77 | ALDH1A1 (0.46) | ALDH1A1LMNATP53CYP3A4TSHR | |
| SCHEMBL24747126 | 0.73 | SQOR (0.44) | ALDH1A1LMNATP53CYP3A4KDM4E | |
| SCHEMBL13394233 | 0.73 | GABRA1 (0.41) | ALDH1A1CYP3A4 | |
| SCHEMBL15119647 | 0.72 | GABRA1 (0.47) | KDM4EATMTUBB1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361568-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2013-01-29 | — | — | US | disclosed |
| US-20100102275-A1 | LIQUID-CRYSTALLINE MEDIUM | KLASEN-MEMMER MELANIE | 2010-04-29 | — | — | US | disclosed |