Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18951853 | 0.80 | ALDH1A1 (0.46) | TSHRALDH1A1THRBCA1 | |
| SCHEMBL566391 | 0.80 | GABRR1 (0.48) | TSHRALDH1A1THRBNOS3NOS1 | |
| SCHEMBL10638508 | 0.80 | ALDH1A1 (0.41) | TSHRALDH1A1ALOX15THRBCHRNB2 | |
| SCHEMBL30401063 | 0.79 | MEN1 (0.44) | TSHRALDH1A1THRBCHRNB2CHRNB4 | |
| SCHEMBL30103441 | 0.79 | CA2 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA4CA2 | |
| SCHEMBL29672786 | 0.77 | — | — | |
| SCHEMBL310765 | 0.77 | — | — | |
| SCHEMBL29219064 | 0.77 | ALDH1A1 (0.48) | TSHRALDH1A1THRBNOS3NOS1 | |
| SCHEMBL28943090 | 0.77 | TSHR (0.47) | TSHRALDH1A1THRBCHRNB2CHRNB4 | |
| SCHEMBL27481944 | 0.77 | ALDH1A1 (0.39) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100513386-C | Amides for inhibiting interleukin 8-induced chemotaxis of neutrophils | DOMP S P A (IT) | 2009-07-15 | — | — | CN | disclosed |