Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310765 | 0.87 | — | — | |
| SCHEMBL30401063 | 0.84 | MEN1 (0.44) | NOS3NOS1NOS2MEN1KMT2A | |
| SCHEMBL13566434 | 0.82 | MEN1 (0.34) | CA2NOS3NOS1NOS2MEN1 | |
| SCHEMBL8501680 | 0.82 | MEN1 (0.34) | CA2NOS3NOS1NOS2MEN1 | |
| SCHEMBL28290131 | 0.82 | TSHR (0.42) | NOS3NOS1NOS2MEN1KMT2A | |
| SCHEMBL27779653 | 0.79 | TSHR (0.40) | CA2NOS3NOS1NOS2CHRNB2 | |
| SCHEMBL2097809 | 0.79 | ALDH1A1 (0.39) | CA2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12513571 | 0.76 | MGAM (0.34) | MEN1KMT2A | |
| SCHEMBL3236104 | 0.76 | CA2 (0.33) | CA2NOS3NOS1NOS2 | |
| Isobutyramide SCHEMBL28185255 | 0.75 | ALDH1A1 (0.36) | CA2CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097138-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | Avila Therapeutics, Inc. (US) | 2022-12-07 | — | — | EP | disclosed |