Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | FABP1 | P07148 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ACP1 | P24666 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | IL1RN | P18510 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144517 | 0.81 | MAPT (0.47) | CA2CA12CA9FABP1MAPT | |
| SCHEMBL8445072 | 0.78 | ALDH1A1 (0.53) | CA2CA12CA9FABP1MAPT | |
| SCHEMBL27548656 | 0.77 | CA2 (0.43) | CA2CA12CA9MAPTALDH1A1 | |
| SCHEMBL6478505 | 0.75 | MAPT (0.41) | CA2CA12CA9FABP1MAPT | |
| SCHEMBL6477872 | 0.73 | ALDH1A1 (0.47) | CA2CA12CA9FABP1MAPT | |
| Sulfuric Acid SCHEMBL10976515 | 0.72 | CA2 (0.50) | CA2CA12CA9MAPTACP1 | |
| SCHEMBL1956114 | 0.72 | CA2 (0.61) | CA2CA12CA9MAPTACP1 | |
| SCHEMBL8768517 | 0.72 | CA12 (0.51) | CA2CA12CA9ALDH1A1CA1 | |
| SCHEMBL5106885 | 0.72 | CA1 (0.43) | CA2CA12CA9FABP1ALDH1A1 | |
| SCHEMBL11778551 | 0.72 | ALDH1A1 (0.41) | CA2CA12CA9FABP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101795662-B | UV filter capsule | MERCK PATENT GMBH | 2013-01-02 | — | — | CN | disclosed |
| CN-101795733-A | tyrosinase inhibitors | MERCK PATENT GMBH | 2010-08-04 | — | — | CN | disclosed |
| CN-101795662-A | UV filter capsule | MERCK PATENT GMBH | 2010-08-04 | — | — | CN | disclosed |
| CN-101641080-A | Use of chroman-4-one derivatives | MERCK PATENT GMBH DE | 2010-02-03 | — | — | CN | disclosed |
| CN-101588722-A | The antimicrobial compositions that comprises zinc oxide, barium sulfate and silver ion | MERCK PATENT GMBH (DE) | 2009-11-25 | — | — | CN | disclosed |