Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | FABP1 | P07148 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445072 | 0.89 | ALDH1A1 (0.53) | MAPTALDH1A1CA12CA2CA9 | |
| SCHEMBL6478505 | 0.86 | MAPT (0.41) | MAPTALDH1A1CA12CA2CA9 | |
| SCHEMBL6477872 | 0.84 | ALDH1A1 (0.47) | MAPTALDH1A1CA12CA2CA9 | |
| SCHEMBL4824425 | 0.82 | APP (0.39) | MAPTALDH1A1CA12CA2CA9 | |
| SCHEMBL6277903 | 0.81 | ALDH1A1 (0.47) | MAPTALDH1A1CA12CA2CA9 | |
| SCHEMBL27779751 | 0.81 | CA2 (0.46) | MAPTALDH1A1CA12CA2CA9 | |
| Sulfuric Acid SCHEMBL8501572 | 0.77 | ALDH1A1 (0.42) | MAPTALDH1A1CA12CA2CA9 | |
| SCHEMBL5106885 | 0.76 | CA1 (0.43) | ALDH1A1CA12CA2CA9CA1 | |
| Sulfuric Acid SCHEMBL8501322 | 0.76 | MAPT (0.41) | MAPTALDH1A1CA12CA2CA9 | |
| SCHEMBL7883074 | 0.76 | SMN1; SMN2 (0.40) | MAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518408-B1 | Fiber-reactive group is not 2-( beta -sulfatoethylsulfonyl)ethylamino when K1 and K2 are phenyl substituted by a fiber-reactive group, and the fiber-reactive group is not beta -sulfatoethylsulfonyl when K1 and K2 are N-( | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-02-11 | — | — | US | claimed |
| US-6518408-B1 | Fiber-reactive group is not 2-( beta -sulfatoethylsulfonyl)ethylamino when K1 and K2 are phenyl substituted by a fiber-reactive group, and the fiber-reactive group is not beta -sulfatoethylsulfonyl when K1 and K2 are N-( | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-02-11 | — | — | US | disclosed |
| US-6518408-B1 | Fiber-reactive group is not 2-( beta -sulfatoethylsulfonyl)ethylamino when K1 and K2 are phenyl substituted by a fiber-reactive group, and the fiber-reactive group is not beta -sulfatoethylsulfonyl when K1 and K2 are N-( | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-02-11 | — | — | US | disclosed |
| EP-1095105-B1 | REACTIVE COLORANTS, PRODUCTION AND USE THEREOF | CIBA SC HOLDING AG (CH) | 2003-01-29 | — | — | EP | disclosed |
| EP-1095105-A1 | REACTIVE COLORANTS, PRODUCTION AND USE THEREOF | Ciba SC Holding AG (CH) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000004099-A1 | REACTIVE COLORANTS, PRODUCTION AND USE THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-01-27 | — | — | WO | disclosed |
| US-5332813-A | Process for the continuous reaction of difluorotriazinyl compounds with amines | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-26 | — | — | US | disclosed |
| US-5194607-A | REACTIVE DYES WITH A TRIPHENDIOXAZINE CHROMOPHORE | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| US-5136028-A | Red; colorfastness | CIBA-GEIGY CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| US-4652634-A | Water-soluble monoazo compounds containing a N-(sulfoalkyl)-aniline coupling component and a fiber-reactive group of the vinylsulfonyl series in the phenyl or benzothiazole diazo component, suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |
| US-4283196-A | FIXING BY ACTION OF AN ALKALINE AGENT | AMERICAN HOECHST CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |
| US-4271072-A | FIBER-REACTIVE, FOR DYEING NATURAL AND SYNTHETIC POLYAMIDES AND CELULOSES | AMERICAN HOECHST CORPORATION (US) | 1981-06-02 | — | — | US | disclosed |