Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 7/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 2/20 | 0.35 |
| ▸ | CPT1A | P50416 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27780282 | 0.86 | GRM5 (0.44) | HTR2B | |
| SCHEMBL24015824 | 0.86 | HTR2B (0.40) | GCKHTR2B | |
| SCHEMBL27758908 | 0.85 | PREP (0.38) | PRCPHTR2BKDM4ECPT2CPT1A | |
| SCHEMBL1293292 | 0.83 | HTR2B (0.42) | PRCPHTR2B | |
| SCHEMBL934063 | 0.83 | HTR2B (0.42) | PRCPHTR2B | |
| SCHEMBL27758911 | 0.81 | AADAT (0.49) | PRCPHTR2BKDM4E | |
| SCHEMBL25591844 | 0.81 | RIPK1 (0.53) | PRCPHTR2B | |
| SCHEMBL47019 | 0.79 | ALDH1A1 (0.46) | KDM4E | |
| SCHEMBL239739 | 0.79 | ALDH1A1 (0.46) | KDM4E | |
| SCHEMBL34474164 | 0.79 | ALDH1A1 (0.46) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101558059-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-12-03 | — | — | CN | claimed |
| CN-101558059-A | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | CN | claimed |