SCHEMBL27780348

SCHEMBL27780348

C#CNc1ccccc1.[SiH4]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
TDP1 Q9NUW8 4/20 0.43
HSD17B10 Q99714 4/20 0.43
CTSD P07339 1/20 0.43
TSHR P16473 3/20 0.41
PTGS2 P35354 2/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC6A2 P23975 1/20 0.41
MAPK1 P28482 1/20 0.41
HTR2B P41595 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP3A4 P08684 4/20 0.39
CYP1A2 P05177 3/20 0.39
CYP2D6 P10635 3/20 0.39
IDO1 P14902 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27820487 1.00 ALDH1A1 (0.43) ALDH1A1TDP1HSD17B10CTSDTSHR
Benzene SCHEMBL28686547 0.97 ALDH1A1 (0.45) ALDH1A1TDP1HSD17B10CTSDTSHR
SCHEMBL465339 0.97
Hydrochloric Acid SCHEMBL29730399 0.94 ALDH1A1 (0.43) ALDH1A1TDP1HSD17B10CTSDTSHR
SCHEMBL1358827 0.90 ALDH1A1 (0.39) ALDH1A1TDP1HSD17B10CTSDTSHR
SCHEMBL28126651 0.90 TSHR (0.42) ALDH1A1TDP1HSD17B10CTSDTSHR
Chlorobenzene SCHEMBL28705277 0.85 TSHR (0.50) ALDH1A1TDP1HSD17B10CTSDTSHR
Fluorobenzene SCHEMBL28932894 0.85 NOX1 (0.38) ALDH1A1TDP1HSD17B10CTSDTSHR
Iodobenzene SCHEMBL28686568 0.85 ALDH1A1 (0.36) ALDH1A1TDP1HSD17B10CTSDTSHR
Bromobenzene SCHEMBL29087862 0.85 ALDH1A1 (0.50) ALDH1A1TDP1HSD17B10CTSDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106566194-B A kind of high-temperature-resistant epoxy resin 苏州圣杰特种树脂有限公司 2019-01-22 CN claimed
CN-106566194-A High temperature-resistant epoxy resin 苏州圣杰特种树脂有限公司 2017-04-19 CN claimed
CN-102504211-B preparation method of thermoset imide resin modified silazane and its composite material UNIV EAST CHINA SCIENCE & TECH 2014-04-30 CN claimed
CN-102504211-A Thermoset imide resin modified silazane and preparation method of composite material thereof UNIV EAST CHINA SCIENCE & TECH 2012-06-20 CN claimed
CN-102212079-A Novel silazane-tri(ethynylphenylamine)-silicane and method for preparing same UNIV EAST CHINA SCIENCE & TECH 2011-10-12 CN claimed
CN-102190679-A Novel silazane-tetra(acetylenylaniline)-silane and preparation method thereof UNIV EAST CHINA SCIENCE & TECH 2011-09-21 CN claimed
CN-106566194-B A kind of high-temperature-resistant epoxy resin 苏州圣杰特种树脂有限公司 2019-01-22 CN disclosed
CN-106566194-B A kind of high-temperature-resistant epoxy resin 苏州圣杰特种树脂有限公司 2019-01-22 CN disclosed
CN-106566194-A High temperature-resistant epoxy resin 苏州圣杰特种树脂有限公司 2017-04-19 CN disclosed
CN-103724627-B Polysilazane-aniline acetylene-terminated polysilazane and preparation method thereof 华东理工大学 2017-02-15 CN disclosed
CN-102504211-B preparation method of thermoset imide resin modified silazane and its composite material UNIV EAST CHINA SCIENCE & TECH 2014-04-30 CN disclosed
CN-103724627-A Synthesis of novel aminophenylacetenyl-terminated polysilazane UNIV EAST CHINA SCIENCE & TECH 2014-04-16 CN disclosed
CN-102504211-A Thermoset imide resin modified silazane and preparation method of composite material thereof UNIV EAST CHINA SCIENCE & TECH 2012-06-20 CN disclosed
CN-102212079-A Novel silazane-tri(ethynylphenylamine)-silicane and method for preparing same UNIV EAST CHINA SCIENCE & TECH 2011-10-12 CN disclosed
CN-102190679-A Novel silazane-tetra(acetylenylaniline)-silane and preparation method thereof UNIV EAST CHINA SCIENCE & TECH 2011-09-21 CN disclosed
CN-101709062-A Novel silazane-diacetylene aniline silane and preparation method thereof UNIV EAST CHINA SCIENCE & TECH 2010-05-19 CN disclosed