Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL465339 | 0.88 | — | — | |
| Benzene SCHEMBL28686547 | 0.88 | ALDH1A1 (0.45) | TSHRDEPTORMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29730399 | 0.85 | ALDH1A1 (0.43) | TSHRDEPTORMAPTMEN1KMT2A | |
| SCHEMBL27780348 | 0.85 | ALDH1A1 (0.43) | TSHRDEPTORMAPTMEN1KMT2A | |
| SCHEMBL27820487 | 0.85 | ALDH1A1 (0.43) | TSHRDEPTORMAPTMEN1KMT2A | |
| SCHEMBL4756760 | 0.83 | LMNA (0.42) | TSHRNOX1MAPTRAB9ANPC1 | |
| SCHEMBL28126651 | 0.81 | TSHR (0.42) | TSHRNOX1MAPTRAB9ANPC1 | |
| SCHEMBL1358827 | 0.81 | ALDH1A1 (0.39) | TSHRMEN1KMT2ALMNACYP1A2 | |
| Iodobenzene SCHEMBL28686568 | 0.77 | ALDH1A1 (0.36) | TSHRMAPTMEN1KMT2ALMNA | |
| Bromobenzene SCHEMBL29087862 | 0.77 | ALDH1A1 (0.50) | TSHRMAPTRAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057623-B | N-naphthyl indole derivative and synthesis method thereof | 湖南第一师范学院 | 2023-07-21 | — | — | CN | disclosed |
| CN-114057623-A | N-naphthyl indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-18 | — | — | CN | disclosed |