Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27911308 | 0.72 | MMP8 (0.48) | TSHRSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL11194919 | 0.71 | SOAT1 (0.48) | TSHRLMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10693813 | 0.69 | HTT (0.35) | TSHRLMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3599329 | 0.68 | MGAM (0.39) | MRGPRX4LMNAMAPK1MEN1KMT2A | |
| SCHEMBL5816889 | 0.68 | MMP8 (0.40) | TSHRMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1643715 | 0.67 | POLB (0.42) | TSHRMRGPRX4LMNAMAPTSMN1; SMN2 | |
| SCHEMBL1643713 | 0.67 | POLB (0.42) | TSHRMRGPRX4LMNAMAPTSMN1; SMN2 | |
| SCHEMBL29364351 | 0.67 | POLB (0.42) | TSHRMRGPRX4LMNAMAPTSMN1; SMN2 | |
| SCHEMBL14855852 | 0.66 | PRKCZ (0.49) | LMNAHSD17B2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27859551 | 0.66 | ALDH1A1 (0.37) | MRGPRX4LMNAMAPK1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679359-B | Quinolines and their therapeutic use | ARGENTA DISCOVERY LTD | 2013-03-06 | — | — | CN | disclosed |
| CN-101679359-A | Quinolines and their therapeutic use | ARGENTA DISCOVERY LTD | 2010-03-24 | — | — | CN | disclosed |