Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27759268 | 0.88 | HRH3 (0.40) | GAAELANEPIK3CDSMN1; SMN2HRH3 | |
| SCHEMBL27780658 | 0.81 | KCNH2 (0.40) | ALDH1A1ELANEPIK3CDSMN1; SMN2HRH3 | |
| SCHEMBL27780676 | 0.78 | TNF (0.42) | GAAELANEPIK3CDHRH3KCNK3 | |
| SCHEMBL27759300 | 0.78 | HRH3 (0.42) | GAAPIK3CDHRH3 | |
| SCHEMBL27759292 | 0.78 | HRH3 (0.42) | GAAALDH1A1ELANEPIK3CDSMN1; SMN2 | |
| SCHEMBL27780703 | 0.78 | USP2 (0.37) | ELANESMN1; SMN2HRH3KCNK3LMNA | |
| SCHEMBL27759279 | 0.74 | LMNA (0.31) | GAALMNA | |
| SCHEMBL27780652 | 0.66 | HTT (0.36) | ALDH1A1PIK3CDSMN1; SMN2HRH3LMNA | |
| SCHEMBL28414381 | 0.63 | KMT2A (0.48) | ALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL18904268 | 0.62 | L3MBTL1 (0.45) | ALDH1A1ELANECASRPIK3CDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101535291-A | 5-substituted quinazolinone derivatives as antitumor agents | CELGENE CORP (US) | 2009-09-16 | — | — | CN | disclosed |