Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3323191 | 0.90 | DRD2 (0.52) | DRD2DRD3ACHEMEN1KMT2A | |
| SCHEMBL27802452 | 0.86 | SSTR5 (0.46) | DRD2DRD3MEN1KMT2AKCNH2 | |
| SCHEMBL27780900 | 0.82 | MEN1 (0.51) | ACHEMEN1KMT2ACA12CA1 | |
| SCHEMBL3323699 | 0.81 | DRD2 (0.62) | DRD2DRD3ACHEMEN1KMT2A | |
| SCHEMBL27780878 | 0.79 | CARM1 (0.50) | MEN1KMT2AKCNH2 | |
| SCHEMBL13361813 | 0.79 | DRD2 (0.53) | DRD2DRD3ACHEMEN1KMT2A | |
| SCHEMBL3322725 | 0.77 | MEN1 (0.50) | DRD2DRD3ACHEMEN1KMT2A | |
| SCHEMBL3321651 | 0.73 | PKM (0.61) | ACHEMEN1KMT2ALMNAPKM | |
| SCHEMBL27802446 | 0.70 | CARM1 (0.46) | ACHEMEN1KMT2AKCNH2 | |
| SCHEMBL3659492 | 0.69 | DRD2 (0.46) | DRD2DRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101663299-A | Thia (dia) zoles as fast dissociating dopamine 2 receptor antagonists | JANSSEN PHARMACEUTICA NV | 2010-03-03 | — | — | CN | claimed |
| CN-101663299-A | Thia (dia) zoles as fast dissociating dopamine 2 receptor antagonists | JANSSEN PHARMACEUTICA NV | 2010-03-03 | — | — | CN | disclosed |