Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.43 |
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | EED | O75530 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HLA-A | P04439 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3322725 | 0.89 | MEN1 (0.50) | SSTR5MEN1KMT2AGAADRD2 | |
| SCHEMBL3323699 | 0.79 | DRD2 (0.62) | SSTR5MEN1KMT2AGAADRD2 | |
| SCHEMBL3321651 | 0.78 | PKM (0.61) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL13361813 | 0.78 | DRD2 (0.53) | SSTR5KCNH2MEN1KMT2AGAA | |
| SCHEMBL3323191 | 0.77 | DRD2 (0.52) | SSTR5MEN1KMT2AGAADRD2 | |
| SCHEMBL3322115 | 0.73 | ACHE (0.55) | MEN1KMT2ALMNATP53SLC6A4 | |
| SCHEMBL12993065 | 0.71 | HTR2A (0.59) | HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL3323359 | 0.71 | CXCR3 (0.50) | MEN1KMT2ACHRM4CHRM3DRD4 | |
| SCHEMBL5871773 | 0.68 | KCNH2 (0.62) | SSTR5KCNH2EHMT2DNMT3AHTR2A | |
| SCHEMBL7724043 | 0.68 | HTR2A (0.51) | HTR2AHTR2CHTR7HTR6EED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101663299-A | Thia (dia) zoles as fast dissociating dopamine 2 receptor antagonists | JANSSEN PHARMACEUTICA NV | 2010-03-03 | — | — | CN | claimed |
| CN-101663299-A | Thia (dia) zoles as fast dissociating dopamine 2 receptor antagonists | JANSSEN PHARMACEUTICA NV | 2010-03-03 | — | — | CN | disclosed |