Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346126 | 0.96 | LMNA (0.61) | LMNASMN1; SMN2CA1CA2HTT | |
| SCHEMBL27761091 | 0.83 | SMN1; SMN2 (0.58) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL10662740 | 0.83 | LMNA (0.67) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL27761103 | 0.83 | EPHX2 (0.67) | CA1CA2HTTKMT2AMEN1 | |
| SCHEMBL4348481 | 0.79 | SMN1; SMN2 (0.57) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL4348602 | 0.79 | EPHX2 (0.74) | CA1CA2HTTKMT2AMEN1 | |
| SCHEMBL4350097 | 0.79 | SMN1; SMN2 (0.54) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL4347106 | 0.78 | MAPT (0.68) | LMNASMN1; SMN2CA1CA2HTT | |
| SCHEMBL27782815 | 0.78 | MAPT (0.67) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL10785928 | 0.77 | SMN1; SMN2 (0.71) | LMNASMN1; SMN2HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100546977-C | Suppress the new compound and the application thereof of rotamase | JERINI AG (DE) | 2009-10-07 | — | — | CN | claimed |