Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27782807 | 0.84 | POLB (0.47) | LMNAALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL27761080 | 0.84 | PKM (0.57) | LMNAALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL28784044 | 0.81 | LMNA (0.38) | LMNAALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL27761119 | 0.74 | LMNA (0.43) | LMNAALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL27761068 | 0.74 | MEN1 (0.47) | LMNAALDH1A1HTTRAB9ANPSR1 | |
| SCHEMBL4354007 | 0.74 | NPC1 (0.46) | LMNAALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL4354001 | 0.71 | LMNA (0.62) | LMNAALDH1A1HTTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27633997 | 0.70 | PKM (0.63) | LMNAALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL27782794 | 0.68 | PKM (0.57) | LMNARAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11439774 | 0.67 | ALDH1A1 (0.58) | LMNAALDH1A1HTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100546977-C | Suppress the new compound and the application thereof of rotamase | JERINI AG (DE) | 2009-10-07 | — | — | CN | claimed |