Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 4/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15641739 | 0.79 | HPGD (0.48) | HPGDCYSLTR2CYSLTR1 | |
| SCHEMBL1926388 | 0.76 | KCNA3 (0.48) | SOAT1HPGDKCNA3 | |
| SCHEMBL8780386 | 0.75 | CYSLTR2 (0.58) | PTGER1PTGER4PTGER3PTGER2CYSLTR2 | |
| SCHEMBL368609 | 0.75 | PTGS2 (0.43) | SOAT1 | |
| SCHEMBL6053663 | 0.74 | PTGER4 (0.81) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL9484842 | 0.74 | CYSLTR2 (0.60) | PTGER1PTGER4PTGER3PTGER2CYSLTR2 | |
| SCHEMBL9484846 | 0.73 | PTGER1 (0.62) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL4785901 | 0.73 | BCAT2 (0.51) | SOAT1HPGD | |
| SCHEMBL31212507 | 0.73 | PTGER4 (0.77) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL1261128 | 0.73 | PTGER4 (0.77) | PTGER1PTGER4PTGER3PTGER2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101555211-B | Chemical synthesis method of 2-acylamino-3-biphenyl propionic acid | ZHEJIANG JIUZHOU PHARM CO LTD | 2012-01-25 | — | — | CN | disclosed |
| CN-101774941-A | Method for preparing and splitting 2-acyl amino-3-biphenylyl propionic acid | ZHEJIANG JIUZHOU PHARMACEUTICA | 2010-07-14 | — | — | CN | disclosed |
| CN-101555211-A | Chemical synthesis method of 2-acylamino-3-biphenyl propionic acid | ZHEJIANG JIUZHOU PHARMACEUTICA (CN) | 2009-10-14 | — | — | CN | disclosed |