Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | F2R | P25116 | 2/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259314 | 0.86 | BCAT2 (0.57) | BCAT2LTB4R2ALDH1A1MEN1MAPT | |
| SCHEMBL3708756 | 0.85 | CYP2C9 (0.47) | LTB4R2KDM4ETSHRHTTALOX15 | |
| SCHEMBL3708751 | 0.85 | HTT (0.43) | LTB4R2KDM4ETSHRHTTALDH1A1 | |
| SCHEMBL24074655 | 0.77 | KDM4E (0.47) | BCAT2LTB4R2KDM4ETSHRHTT | |
| SCHEMBL3704895 | 0.77 | CHRNB2 (0.44) | KDM4EHTTALDH1A1HPGDMEN1 | |
| SCHEMBL3704894 | 0.77 | ALDH1A1 (0.48) | BCAT2KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL4785899 | 0.76 | TSHR (0.47) | BCAT2LTB4R2KDM4ETSHRHTT | |
| SCHEMBL2732932 | 0.76 | NAAA (0.51) | KDM4ETSHRHTTALDH1A1HPGD | |
| SCHEMBL27822509 | 0.76 | BCAT2 (0.59) | BCAT2MEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL14577687 | 0.75 | TSHR (0.53) | KDM4ETSHRHTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |