Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 2/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3349207 | 0.79 | CES1 (0.45) | NPC1RAB9ACES1MAPTSMN1; SMN2 | |
| SCHEMBL3349927 | 0.72 | CYP1A2 (0.52) | CES1MAPTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL3345524 | 0.72 | CES1 (0.50) | CES1MAPTSMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL9622340 | 0.69 | CES1 (0.42) | NPC1RAB9ACES1MAPTSMN1; SMN2 | |
| SCHEMBL3345739 | 0.68 | CES1 (0.46) | NPC1RAB9ACES1MAPTSMN1; SMN2 | |
| SCHEMBL9756273 | 0.67 | CES1 (0.45) | PTGS2CES1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29141154 | 0.66 | CYP1A2 (0.42) | SMN1; SMN2CYP1A2CYP2C19EPHX1LMNA | |
| SCHEMBL3767845 | 0.66 | PTGS2 (0.50) | PTGS2ACP3MAPTSMN1; SMN2PRCP | |
| SCHEMBL29242313 | 0.66 | SMN1; SMN2 (0.55) | NPC1RAB9ACTDSP1CES1MAPT | |
| SCHEMBL9561521 | 0.66 | TSHR (0.47) | CYP2C9NPC1CES1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101555211-B | Chemical synthesis method of 2-acylamino-3-biphenyl propionic acid | ZHEJIANG JIUZHOU PHARM CO LTD | 2012-01-25 | — | — | CN | disclosed |
| CN-101555211-A | Chemical synthesis method of 2-acylamino-3-biphenyl propionic acid | ZHEJIANG JIUZHOU PHARMACEUTICA (CN) | 2009-10-14 | — | — | CN | disclosed |