Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27816730 | 0.84 | MAPT (0.37) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7088620 | 0.83 | NPC1 (0.39) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL9952010 | 0.79 | TLR8 (0.38) | RAB9ANPC1ELANE | |
| SCHEMBL16346102 | 0.76 | NPC1 (0.40) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL7088775 | 0.76 | NPC1 (0.41) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL3735368 | 0.76 | RAB9A (0.45) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL3234460 | 0.76 | NPC1 (0.41) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL9690618 | 0.76 | NPC1 (0.41) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL71079 | 0.76 | NPC1 (0.41) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL3859298 | 0.76 | NPC1 (0.41) | RAB9ANPC1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101555226-A | N-benzyl-9, 10- dihydro-acridine compound and preparation method thereof | UNIV TSINGHUA GRADUATE SCHOOL (CN) | 2009-10-14 | — | — | CN | disclosed |