Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27783053 | 0.93 | MEN1 (0.68) | MEN1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL24270332 | 0.90 | MAP4K4 (0.74) | MEN1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL19742855 | 0.82 | RAB9A (1.00) | MEN1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL2643156 | 0.80 | MAP4K4 (1.00) | MEN1NPC1RAB9AMAP4K4MAOA | |
| SCHEMBL21537534 | 0.80 | MAP4K4 (0.59) | MEN1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL27804589 | 0.80 | MAP4K4 (0.66) | MEN1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL250353 | 0.80 | MAOA (0.76) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| Benzidine SCHEMBL29236355 | 0.80 | MAOA (0.76) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL29350106 | 0.80 | MAOA (0.76) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL29115269 | 0.80 | MAOA (0.76) | MEN1ALDH1A1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101735141-A | Hexa-aromatic heterocyclic diamine and preparation method thereof | CHANGCHUN APPLIED CHEMISTRY | 2010-06-16 | — | — | CN | claimed |
| CN-101735141-A | Hexa-aromatic heterocyclic diamine and preparation method thereof | CHANGCHUN APPLIED CHEMISTRY | 2010-06-16 | — | — | CN | disclosed |