SCHEMBL27784191

SCHEMBL27784191

CCc1cncn1C(CC)CC

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.32
DHFR P00374 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19699657 0.81 CYP1A2 (0.33)
SCHEMBL23137839 0.78 CYP1A2 (0.31)
SCHEMBL18250743 0.77 L3MBTL1 (0.36) L3MBTL1
SCHEMBL15202298 0.75 L3MBTL1 (0.32) L3MBTL1
SCHEMBL18250235 0.73 CYP1A2 (0.34) L3MBTL1DHFR
SCHEMBL27762334 0.71
SCHEMBL27762339 0.69 ALDH1A1 (0.41) L3MBTL1
SCHEMBL27811681 0.69 GABRA1 (0.37)
SCHEMBL178520 0.69
SCHEMBL14472515 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102993204-A Certain chemical entities, compositions and methods CYTOKINETICS INC 2013-03-27 CN claimed
CN-101522681-A Specific chemical entities, compositions and methods CYTOKINETICS INC (US) 2009-09-02 CN claimed
CN-102993204-A Certain chemical entities, compositions and methods CYTOKINETICS INC 2013-03-27 CN disclosed
CN-101522681-A Specific chemical entities, compositions and methods CYTOKINETICS INC (US) 2009-09-02 CN disclosed