Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ofloxacin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.98 |
| ▸ | HPGD | P15428 | 4/20 | 0.98 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.98 |
| ▸ | ALB | P02768 | 1/20 | 0.98 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.98 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.96 |
| ▸ | TUBB | P07437 | 7/20 | 0.96 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.96 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.96 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.96 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.96 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.96 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.96 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.96 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.96 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.96 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.96 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.96 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.96 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levofloxacin Anhydrous SCHEMBL30209775 | 1.00 | KDM4E (0.98) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Levofloxacin Anhydrous SCHEMBL554426 | 1.00 | KDM4E (0.98) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Levofloxacin Anhydrous SCHEMBL28565611 | 1.00 | KDM4E (0.98) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Levofloxacin Anhydrous SCHEMBL27549800 | 1.00 | KDM4E (0.98) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Levofloxacin Anhydrous SCHEMBL27810870 | 0.99 | KDM4E (0.98) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Ofloxacin SCHEMBL9745243 | 0.99 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Ofloxacin SCHEMBL14163982 | 0.99 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Levofloxacin Anhydrous SCHEMBL1442440 | 0.99 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Levofloxacin Anhydrous SCHEMBL15397 | 0.99 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Ofloxacin SCHEMBL24373 | 0.99 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120115168-A | Aluminum-based nano-oxidase and preparation method and application thereof | 广东工业大学 | 2025-06-10 | — | — | CN | claimed |
| CN-118256237-A | Preparation method and application of fluorescent carbon quantum dot | 中国石油大学(华东) | 2024-06-28 | — | — | CN | claimed |
| CN-118121709-A | Ophthalmic pharmaceutical composition, and preparation method and application thereof | 山东序列生物科技有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-116459333-A | Medical sealing agent for wound repair and preparation and use methods thereof | 上海利康瑞生物工程有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-109908875-B | Method for removing electropositive drug in sewage | 兰州大学 | 2021-06-15 | — | — | CN | claimed |
| CN-109908875-A | A kind of method of electropositive drug in removal sewage | 兰州大学 | 2019-06-21 | — | — | CN | claimed |
| CN-206304188-U | A kind of Ofloxacin chloride injection device | 广东艾希德药业有限公司 | 2017-07-07 | — | — | CN | claimed |
| CN-104473251-B | A liquid for improving ginseng fruit | 黎明 | 2016-08-24 | — | — | CN | claimed |
| CN-105707147-A | Liquid for reducing eggplant incidence rate and preparation method thereof | 罗国友 | 2016-06-29 | — | — | CN | claimed |
| CN-105707145-A | Liquid for increasing sugar content of solanum muricatum and preparation method of liquid for increasing sugar content of solanum muricatum | 罗国友 | 2016-06-29 | — | — | CN | claimed |
| CN-105707146-A | Liquid for improving eggplant and preparation method thereof | 罗国友 | 2016-06-29 | — | — | CN | claimed |
| CN-105685128-A | Liquid for increasing sugar content and reducing disease incidence of solanum muricatum and preparation method for liquid | 罗国友 | 2016-06-22 | — | — | CN | claimed |
| CN-103656749-B | A kind of compound degradable antibacterial artificial dura mater and preparation method thereof | BEIHUA UNIVERSITY (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-104473251-A | A liquid for improving ginseng fruit | LUO GUOYOU | 2015-04-01 | — | — | CN | claimed |
| CN-102847160-B | Compound quinolone injection for livestock, and preparation method thereof | GUANGDONG DAHUANONG ANIMAL HEALTH PRODUCTS CO LTD | 2014-05-21 | — | — | CN | claimed |
| CN-103585443-A | Composition for treating canine distemper and preparation method for composition | QINGDAO LVMAN BIOLOG ENG CO | 2014-02-19 | — | — | CN | claimed |
| CN-102847160-A | Compound quinolone injection for livestock, and preparation method thereof | GUANGDONG DAHUANONG ANIMAL HEALTH PRODUCTS CO LTD | 2013-01-02 | — | — | CN | claimed |
| CN-120115168-A | Aluminum-based nano-oxidase and preparation method and application thereof | 广东工业大学 | 2025-06-10 | — | — | CN | disclosed |
| WO-2007124479-A2 | AVIAN INFLUENZA VIRUSES, VACCINES, COMPOSITIONS, FORMULATIONS, AND METHODS | WYETH (US) | 2007-11-01 | — | — | WO | disclosed |
| US-20070190109-A1 | IMPLANT MATERIAL | HERAEUS KULZER GMBH (DE) | 2007-08-16 | — | — | US | disclosed |