Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Levofloxacin Anhydrous. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.98 |
| ▸ | HPGD | P15428 | 4/20 | 0.98 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.98 |
| ▸ | ALB | P02768 | 1/20 | 0.98 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.98 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.96 |
| ▸ | TUBB | P07437 | 7/20 | 0.96 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.96 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.96 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.96 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.96 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.96 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.96 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.96 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.96 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.96 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.96 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.96 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.96 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ofloxacin SCHEMBL2778451 | 1.00 | KDM4E (0.98) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Levofloxacin Anhydrous SCHEMBL30209775 | 1.00 | KDM4E (0.98) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Levofloxacin Anhydrous SCHEMBL28565611 | 1.00 | KDM4E (0.98) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Levofloxacin Anhydrous SCHEMBL27549800 | 1.00 | KDM4E (0.98) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Levofloxacin Anhydrous SCHEMBL27810870 | 0.99 | KDM4E (0.98) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Ofloxacin SCHEMBL9745243 | 0.99 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Ofloxacin SCHEMBL14163982 | 0.99 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Levofloxacin Anhydrous SCHEMBL1442440 | 0.99 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Levofloxacin Anhydrous SCHEMBL15397 | 0.99 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Ofloxacin SCHEMBL24373 | 0.99 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120189951-A | CoMoO4/BiVO4Nanometer material, preparation method and application | 大连医科大学 | 2025-06-24 | — | — | CN | claimed |
| CN-120118096-A | Synthesis and purification method of levofloxacin hydrochloride | 江西大地制药有限责任公司 | 2025-06-10 | — | — | CN | claimed |
| CN-120115168-A | Aluminum-based nano-oxidase and preparation method and application thereof | 广东工业大学 | 2025-06-10 | — | — | CN | claimed |
| CN-119970661-A | Levofloxacin tablet and preparation method thereof | 重庆药谷制药有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119857506-A | Cu for removing antibiotics in water2Preparation method of O/black phosphorus catalyst | 大连医科大学 | 2025-04-22 | — | — | CN | claimed |
| CN-119750241-A | Equipment and method for adding levofloxacin hydrochloride preparation raw materials at fixed time and fixed quantity | 河南康达制药有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-118987375-B | Drug-loaded medical instrument, drug coating, and preparation methods and applications thereof | 真健康(广东横琴)医疗科技有限公司 | 2025-01-14 | — | — | CN | claimed |
| CN-119258133-A | Application of traditional Chinese medicine composition in preparation of medicines for treating and/or preventing bronchitis | 江苏康缘药业股份有限公司 | 2025-01-07 | — | — | CN | claimed |
| CN-119119463-A | Cobalt phthalocyanine with defect structure and preparation method and application thereof | 湖南大学 | 2024-12-13 | — | — | CN | claimed |
| CN-119055657-A | Use of ofloxacin or derivatives thereof in the preparation of inhibitors of extracellular vesicle secretion | 武汉大学 | 2024-12-03 | — | — | CN | claimed |
| CN-1813758-A | Levofloxacin hydrochloride micro-pill capsule and its preparing method | FAN MINHUA (CN) | 2006-08-09 | — | — | CN | claimed |
| CN-1785431-A | Adjuvant of slow release agent used for eye and medicine containing said adjurant and its preparation method | CHENGDU SAMING MEDICINE INST (CN) | 2006-06-14 | — | — | CN | claimed |
| CN-1634073-A | Orally disintegrating tablet of levofloxacin and its pharmaceutical salt | BEIJING FU KANG REN BIO PHARM (CN) | 2005-07-06 | — | — | CN | claimed |
| CN-1634072-A | Levofloxacin dripping pills and its preparing process | PENG HONG (CN) | 2005-07-06 | — | — | CN | claimed |
| CN-1616104-A | Transfusion medicine prepared from xylitol as istonic regulator and various injections separately and its preparing method | CUI XIAOTING (CN) | 2005-05-18 | — | — | CN | claimed |
| CN-1579402-A | Medicinal composition for treating bacterial conjunctivitis and keratitis and preparation and preparation method | SANMING MEDICINE INST CHENGDU (CN) | 2005-02-16 | — | — | CN | claimed |
| US-20040253314-A1 | Melt extrusion of salts of active ingredients | ROEHM GMBH (DE) | 2004-12-16 | — | — | US | claimed |
| CN-1552327-A | Oral ofloxacin control-sustained releasing medicinal composition | 江苏豪森药业股份有限公司 | 2004-12-08 | — | — | CN | claimed |
| EP-1478344-A2 | MELT EXTRUSION CONSISTING OF SALTS OF ACTIVE INGREDIENTS | Röhm GmbH & Co. KG (DE) | 2004-11-24 | — | — | EP | claimed |
| WO-2003072083-A2 | MELT EXTRUSION CONSISTING OF SALTS OF ACTIVE INGREDIENTS | Röhm GmbH & Co. KG (DE) | 2003-09-04 | — | — | WO | claimed |