Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648992 | 0.81 | CYP11B1 (0.48) | CYP11B2CYP11B1TSHR | |
| SCHEMBL27806613 | 0.79 | KIF11 (0.47) | KIF11CYP11B2MMP3ALDH1A1CYP2A6 | |
| SCHEMBL21899532 | 0.79 | KIF11 (0.47) | KIF11CYP11B2MMP3ALDH1A1CYP2A6 | |
| SCHEMBL25871771 | 0.79 | ALDH1A1 (0.48) | CYP11B2ALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL23958923 | 0.77 | MAOB (0.43) | KIF11CYP11B2MMP3ALDH1A1CYP2A6 | |
| SCHEMBL7634772 | 0.77 | ALDH1A1 (0.48) | KIF11CYP11B2MMP3ALDH1A1CYP2A6 | |
| SCHEMBL14524914 | 0.76 | AR (0.44) | KIF11CYP11B2MMP3ALDH1A1CYP2A6 | |
| SCHEMBL14499523 | 0.76 | KDM1A (0.45) | CYP11B2ALDH1A1CYP2A6CA12CA1 | |
| SCHEMBL29306055 | 0.75 | ALDH1A1 (0.57) | KIF11CYP11B2MMP3ALDH1A1CYP2A6 | |
| SCHEMBL17630042 | 0.75 | MAOB (0.43) | KIF11CYP11B2MMP3ALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101759648-A | Terphenyl bridged double-benzimidazole compound, and synthesis method and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2010-06-30 | — | — | CN | disclosed |