Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 8/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 4/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13001686 | 0.83 | TSHR (0.52) | CYP11B1CYP11B2ARS1PR1EGLN2 | |
| SCHEMBL7648994 | 0.81 | CYP11B1 (0.46) | CYP11B1CYP11B2ARS1PR1EGLN2 | |
| SCHEMBL27784607 | 0.81 | KIF11 (0.43) | CYP11B1CYP11B2TSHR | |
| SCHEMBL26391852 | 0.80 | AR (0.53) | CYP11B1CYP11B2ARS1PR1EGLN2 | |
| SCHEMBL21188814 | 0.79 | TSHR (0.55) | CYP11B1CYP11B2AREGLN2TSHR | |
| SCHEMBL14173712 | 0.78 | AR (0.50) | CYP11B1CYP11B2ARPGR | |
| SCHEMBL26391841 | 0.76 | AR (0.61) | CYP11B1CYP11B2ARS1PR1EGLN2 | |
| SCHEMBL8338719 | 0.76 | AR (0.61) | CYP11B1CYP11B2ARS1PR1EGLN2 | |
| SCHEMBL119203 | 0.76 | TSHR (0.50) | ARS1PR1EGLN2TSHR | |
| SCHEMBL29306060 | 0.75 | CYP11B1 (0.41) | CYP11B1CYP11B2ARS1PR1EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102738-B1 | METHOD FOR THE ACIDIC OR ALKALINE SAPONIFICATION OF BIPHENYL NITRILES | LEHMANN BERND DR (DE) | 2002-12-04 | — | — | EP | disclosed |
| EP-1102738-A1 | METHOD FOR THE ACIDIC OR ALKALINE SAPONIFICATION OF BIPHENYL NITRILES | Great Lakes Chemical Konstanz GmbH (DE) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000003964-A1 | METHOD FOR THE ACIDIC OR ALKALINE SAPONIFICATION OF BIPHENYL NITRILES | GREAT LAKES CHEMICAL KONSTANZ GMBH (DE) | 2000-01-27 | — | — | WO | disclosed |