Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 2/20 | 0.34 |
| ▸ | PGK2 | P07205 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27979918 | 0.75 | TLR9 (0.36) | CA12MMP2CA9MMP8CA1 | |
| SCHEMBL7107937 | 0.75 | TLR9 (0.39) | CA12MMP2CA9MMP8CA1 | |
| SCHEMBL27815255 | 0.74 | GLA (0.37) | LMNANPSR1 | |
| SCHEMBL27592268 | 0.73 | TLR9 (0.38) | CA12MMP2CA9MMP8CA1 | |
| SCHEMBL27784840 | 0.73 | CA12 (0.42) | CA12MMP2CA9CA14MMP8 | |
| SCHEMBL27918899 | 0.68 | GRIA4 (0.36) | CA12MMP2CA9MMP8CA1 | |
| SCHEMBL27513087 | 0.68 | LMNA (0.49) | CA12CA9LMNAMMP1NPSR1 | |
| SCHEMBL18300580 | 0.67 | CA12 (0.49) | CA12MMP2CA9CA14MMP8 | |
| SCHEMBL16346863 | 0.66 | ALDH1A1 (0.53) | CA12MMP2CA9CA14MMP8 | |
| SCHEMBL27572608 | 0.66 | CA1 (0.46) | CA1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101591281-A | Phosphonate compounds having immunomodulatory activity | GILEAD SCIENCES INC (US) | 2009-12-02 | — | — | CN | disclosed |