Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 6/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27786050 | 0.90 | GABRG2 (0.35) | GABRG2GABRB3GABRA2KDM1A | |
| SCHEMBL27786064 | 0.89 | GABRG2 (0.34) | GABRG2GABRB3GABRA2KDM1A | |
| SCHEMBL27807955 | 0.86 | SSTR2 (0.33) | GABRG2GABRB3GABRA2KDM1A | |
| SCHEMBL27807983 | 0.86 | GABRG2 (0.33) | GABRG2GABRB3GABRA2KDM1A | |
| SCHEMBL27807952 | 0.86 | GABRG2 (0.34) | GABRG2GABRB3GABRA2KDM1A | |
| SCHEMBL27807932 | 0.83 | GABRG2 (0.41) | GABRG2GABRB3GABRA2 | |
| SCHEMBL28784319 | 0.82 | GABRG2 (0.39) | GABRG2GABRB3GABRA2 | |
| SCHEMBL27785943 | 0.80 | GABRG2 (0.33) | GABRG2GABRB3GABRA2KDM1A | |
| SCHEMBL27807963 | 0.80 | GABRG2 (0.50) | GABRG2GABRB3GABRA2 | |
| SCHEMBL27807926 | 0.79 | ALDH1A1 (0.31) | GABRG2GABRB3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778849-A | Fused quinoline derivatives useful as gaba modulators | ASTRAZENECA AB | 2010-07-14 | — | — | CN | claimed |
| CN-101778849-A | Fused quinoline derivatives useful as gaba modulators | ASTRAZENECA AB | 2010-07-14 | — | — | CN | disclosed |