Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1420780 | 0.97 | ACHE (0.31) | ACHELMNAALDH1A1NPC1TSHR | |
| SCHEMBL23779832 | 0.89 | HPGD (0.35) | LMNAALDH1A1TSHRHPGD | |
| SCHEMBL14938745 | 0.83 | — | — | |
| SCHEMBL23355925 | 0.83 | — | — | |
| SCHEMBL1936310 | 0.76 | HSD11B1 (0.37) | ACHEALDH1A1NPC1TSHRHPGD | |
| SCHEMBL2738424 | 0.75 | CYP1A2 (0.48) | ALDH1A1 | |
| SCHEMBL8309136 | 0.74 | HSD11B1 (0.36) | ACHELMNAALDH1A1NPC1 | |
| SCHEMBL146591 | 0.74 | MAPT (0.37) | LMNAALDH1A1TSHRHPGD | |
| SCHEMBL1934485 | 0.74 | DPP4 (0.37) | ACHELMNAALDH1A1NPC1TSHR | |
| SCHEMBL169000 | 0.74 | GRM5 (0.42) | ACHELMNANPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101795567-A | New heteocyclic H3 antagonists | HIGH POINT PHARMACEUTICALS LLC | 2010-08-04 | — | — | CN | disclosed |