Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.34 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936310 | 0.97 | HSD11B1 (0.37) | HSD11B1GNAI3GNAO1GNAI1GPR119 | |
| SCHEMBL23089850 | 0.90 | HSD11B1 (0.46) | HSD11B1EPHX2L3MBTL3MBTD1ITGB3 | |
| SCHEMBL20668089 | 0.87 | MBTD1 (0.46) | HSD11B1EPHX2L3MBTL3MBTD1ITGB3 | |
| SCHEMBL29143116 | 0.87 | HSD11B1 (0.44) | HSD11B1GNAI3GNAO1GNAI1GPR119 | |
| SCHEMBL3723280 | 0.85 | HSD11B1 (0.33) | HSD11B1GNAI3GNAO1GNAI1GPR119 | |
| SCHEMBL144841 | 0.84 | GNAI3 (0.50) | GNAI3GNAO1GNAI1L3MBTL3MBTD1 | |
| SCHEMBL4473669 | 0.84 | L3MBTL3 (0.44) | L3MBTL3MBTD1L3MBTL1ALDH1A1 | |
| SCHEMBL30484935 | 0.84 | CHRNB2 (0.44) | GNAI3GNAO1GNAI1L3MBTL3L3MBTL1 | |
| SCHEMBL28824435 | 0.82 | GPR119 (0.33) | HSD11B1GNAI3GNAO1GNAI1GPR119 | |
| SCHEMBL4474282 | 0.80 | SMN1; SMN2 (0.50) | HSD11B1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1238765-A | N-(imidazoly (butyl) benzenesulphonamide derivatives with anticoagulation active | SYNTHEBLABO (FR) | 1999-12-15 | — | — | CN | disclosed |
| EP-0946517-A1 | N-(IMIDAZOLYLBUTYL) BENZENESULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATION | SYNTHELABO (FR) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998022443-A1 | N-(IMIDAZOLYLBUTYL) BENZENESULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATION | SYNTHELABO (FR) | 1998-05-28 | — | — | WO | disclosed |